The effects of inflammation on neurotransmitter production (reduced serotonin production, increased quinolinic acid production) also create a tendency towards mood and behavioural changes, often diagnosed as depression and anxiety
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This supports the idea that insulin resistance (IR) and chronic inflammation contribute to the overlapping aetiologies of T2DM and PD
The letter L refers to the amino-acid configuration
To provide a comprehensive yet structured overview of key oxidative stress-related biomarkers in MASLD, Tables II and III summarize their mechanistic roles, therapeutic relevance, biological sources, detection methods, clinical utility, and limitations